The Popkin Method
You’re not crazy. Your care is just fragmented. Most people bounce between specialists, apps, and online “biohacks” without ever getting real answers.
The Popkin Method is here to change that - with real, physician-led medicine that integrates the best of internal and functional approaches into one clear, personalized care.
Hosted by Matthew C. Popkin, M.D., an Internal Medicine specialist with surgical training and functional medicine expertise - this podcast explores how to reconnect the dots between your symptoms, labs, lifestyle, and deeper health goals.
Whether you're battling fatigue, inflammation, hormones, weight, or aging - this show delivers clinical insight, clarity, and next steps… with none of the hype.
Real medicine. Real results. Real transformation.
OUR PODCAST
Latest Episodes
Beyond Peptides: Building a Lasting Weight Loss Foundation with the Popkin Method
Welcome to The Popkin Method, where we cut through the noise of miracle weight loss solutions and trendy shortcuts dominating social media and advertising today. In this episode, Dr. Matthew C. Popkin takes a deep, clinical dive into GLP-1-based therapies like semaglutide and tirzepatide, some of th...
Demystifying Fatty Liver Disease: The Four-Phase Popkin Method for Sustainable Metabolic Health
Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the most misunderstood, yet critical, obstacles to lasting weight loss and wellness: fatty liver disease. Most people think of it as just a byproduct of poor diet or being overweight, but as you’ll learn toda...
Unlocking the Cellular Secrets of Aging: How NAD Fuels Longevity from the Inside Out
Welcome back to The Popkin Method! In this episode, Dr. Matthew C. Popkin takes us beyond the surface of anti-aging, exploring the science of aging from the inside out. We’re all familiar with visible signs like wrinkles and graying hair, but what really drives aging happens deep within our cells. D...
Building Sustainable Care Plans: The Popkin Method Approach to Lasting Health
Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the biggest challenges in modern healthcare: making care plans that truly stick. Most people don’t fail their health plans; the plans fail them, often because they’re too complex, reactive, or fragmented. Ins...
Demystifying Hormone Optimization Therapy for Men and Women with the Popkin Method
Welcome to another episode of The Popkin Method, where we’re passionate about restoring physiology, preserving lean muscle mass, stabilizing your metabolism, and building long-term resilience from the inside out. This week, Dr. Popkin tackles one of the most misunderstood and sought after topics in ...
Reversing Chronic Inflammation: The Popkin Method’s Three-Phase Approach for Better Health
Welcome back to The Popkin Method! In this episode, host Dr. Matthew C. Popkin dives deep into one of the most important yet misunderstood topics in modern health: whole body systemic inflammation. You’ll discover what chronic inflammation really is, how it subtly wreaks havoc on everything from met...



