The Popkin Method

The Popkin Method

You’re not crazy. Your care is just fragmented. Most people bounce between specialists, apps, and online “biohacks” without ever getting real answers.

The Popkin Method is here to change that - with real, physician-led medicine that integrates the best of internal and functional approaches into one clear, personalized care.

Hosted by Matthew C. Popkin, M.D., an Internal Medicine specialist with surgical training and functional medicine expertise - this podcast explores how to reconnect the dots between your symptoms, labs, lifestyle, and deeper health goals.

Whether you're battling fatigue, inflammation, hormones, weight, or aging - this show delivers clinical insight, clarity, and next steps… with none of the hype.

Real medicine. Real results. Real transformation.

OUR PODCAST

Latest Episodes

Beyond Peptides: Building a Lasting Weight Loss Foundation with the Popkin Method
The Popkin MethodMay 29, 2026x
15
00:55:4738.34 MB

Beyond Peptides: Building a Lasting Weight Loss Foundation with the Popkin Method

Welcome to The Popkin Method, where we cut through the noise of miracle weight loss solutions and trendy shortcuts dominating social media and advertising today. In this episode, Dr. Matthew C. Popkin takes a deep, clinical dive into GLP-1-based therapies like semaglutide and tirzepatide, some of th...

Demystifying Fatty Liver Disease: The Four-Phase Popkin Method for Sustainable Metabolic Health
The Popkin MethodMay 20, 2026x
14
01:13:4050.61 MB

Demystifying Fatty Liver Disease: The Four-Phase Popkin Method for Sustainable Metabolic Health

Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the most misunderstood, yet critical, obstacles to lasting weight loss and wellness: fatty liver disease. Most people think of it as just a byproduct of poor diet or being overweight, but as you’ll learn toda...

Unlocking the Cellular Secrets of Aging: How NAD Fuels Longevity from the Inside Out
The Popkin MethodApril 30, 2026x
13
00:53:4036.88 MB

Unlocking the Cellular Secrets of Aging: How NAD Fuels Longevity from the Inside Out

Welcome back to The Popkin Method! In this episode, Dr. Matthew C. Popkin takes us beyond the surface of anti-aging, exploring the science of aging from the inside out. We’re all familiar with visible signs like wrinkles and graying hair, but what really drives aging happens deep within our cells. D...

Building Sustainable Care Plans: The Popkin Method Approach to Lasting Health
The Popkin MethodApril 18, 2026x
12
00:38:0026.13 MB

Building Sustainable Care Plans: The Popkin Method Approach to Lasting Health

Welcome back to The Popkin Method! In today’s episode, Dr. Matthew C. Popkin tackles one of the biggest challenges in modern healthcare: making care plans that truly stick. Most people don’t fail their health plans; the plans fail them, often because they’re too complex, reactive, or fragmented. Ins...

Demystifying Hormone Optimization Therapy for Men and Women with the Popkin Method
The Popkin MethodMarch 27, 2026x
11
00:52:5236.34 MB

Demystifying Hormone Optimization Therapy for Men and Women with the Popkin Method

Welcome to another episode of The Popkin Method, where we’re passionate about restoring physiology, preserving lean muscle mass, stabilizing your metabolism, and building long-term resilience from the inside out. This week, Dr. Popkin tackles one of the most misunderstood and sought after topics in ...

Reversing Chronic Inflammation: The Popkin Method’s Three-Phase Approach for Better Health
The Popkin MethodMarch 13, 2026x
10
00:50:0134.37 MB

Reversing Chronic Inflammation: The Popkin Method’s Three-Phase Approach for Better Health

Welcome back to The Popkin Method! In this episode, host Dr. Matthew C. Popkin dives deep into one of the most important yet misunderstood topics in modern health: whole body systemic inflammation. You’ll discover what chronic inflammation really is, how it subtly wreaks havoc on everything from met...

Meet your Podcast Host

Matthew C. Popkin, M.D. is not your typical physician — and that’s exactly the point. A highly skilled physician with world-class training from the University of Miami School of Medicine, Mount Sinai Medical Center in New York, and the Cleveland Clinic Foundation, Matthew C. Popkin, M.D. spent years mastering internal medicine before realizing something was missing: real results for real people.


Contact Matthew C. Popkin, M.D.

You can schedule an online virtual telemedicine consult with Matthew C. Popkin, M.D. from anywhere in the country or the world for that matter. You can also visit him in his Hollywood Florida office for an in person functional medicine experience. Message Dr. Popkin and his team to schedule an appointment today.

Real Medicine. Real Results
Real Transformation